MINNEAPOLIS — Purilogics, a division of Donaldson Life Sciences, has launched its first manufacturing-grade membrane chromatography product aimed at supporting GMP (Good Manufacturing Practice) processes in the biopharmaceutical sector. The new product, Purexa™ NAEX Prep, is part of the company’s Purexa portfolio and is designed specifically for purifying supercoiled plasmid DNA (pDNA).
The membrane is a weak anion-exchange chromatography consumable that offers high binding capacity with targeted molecules. According to the company, the single-use membrane is compatible with most chromatography systems and allows for simplified setup and breakdown. It is produced in an ISO 9001-certified, Class 7 cleanroom in Bloomington, Minnesota, while research and development takes place at Purilogics’ innovation center in Greenville, South Carolina.
Jin Zhou, Director at Purilogics, said the decision to introduce the NAEX membrane as the company’s first manufacturing-grade product was based on its broad utility. Zhou highlighted three key advantages: high dynamic binding capacity, rapid cycle times, and a scalable format that can reduce processing time and costs when compared to conventional column chromatography.
Purilogics plans to expand its product line through 2025 and 2026, adding both research- and manufacturing-grade offerings. Future releases will include membrane products for mRNA purification, antibody capture, and pDNA polishing. These will be available in a variety of formats, from lab-scale to full-scale manufacturing.
