Wolters Kluwer Outlines Medi-Span Expert AI Initiative to Power Medication Intelligence for Digital Health

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Christopher Sullivan, MBA

WALTHAM, Mass. — Wolters Kluwer Health has unveiled plans for Medi-Span Expert AI, a new initiative aimed at delivering advanced medication intelligence from its Medi-Span platform to digital health technology developers, as demand grows for AI-driven workflows across healthcare.

Medi-Span, developed by the makers of UpToDate and widely used across the healthcare ecosystem, provides drug information designed to support safer and more effective medication decisions. As part of the new initiative, Wolters Kluwer has introduced a Model Context Protocol (MCP) server for select AI developers, intended to reduce development time and complexity by connecting third-party AI applications and agents with AI-ready, expert-curated Medi-Span medication data.

“Agentic workflows from AI-driven prescription renewals to hospital medication verification, represent the fastest-growing segment in healthcare,” said Christopher Sullivan, Vice President and General Manager, Pharmacy and Health Technology Solutions. “Medi-Span Expert AI is being designed to transcend standard content delivery for agents, serving as the foundational intelligence for our customer’s entire medication use lifecycle. From customer’s raw data to its autonomous agents, we expect this new evolution will empower health tech leaders to manage complex workflows and help improve user drug decisions by providing AI ready content via MCP to customers and optimize patient safety solutions.”

According to the company, digital health technology providers are increasingly building agentic AI workflows to meet clinical demand for automation in medication management. Providers and pharmacists are seeking faster, clearer, and more consistent support from clinical systems, while traditional integration methods such as APIs and flat files are often not optimized for AI agent workflows and can slow innovation.

The new MCP server is designed to address these challenges by delivering expert-curated drug content in a fast, dynamic format suitable for AI agents. Wolters Kluwer said this approach can help developers shorten time to innovation while accessing validated medication data, dosing guardrails, and advanced decision logic to support safer clinical and operational workflows.

Looking ahead, the company expects Medi-Span Expert AI to expand across a wide range of AI-enabled clinical, patient, and administrative use cases. Potential applications include clinical decision support, medication order validation and verification, medication lookup and reconciliation, adverse event monitoring, formulary and benefit management, pricing and contracting, as well as inventory and supply chain optimization.

“Wolters Kluwer understands both the technology and patient care side of medication. Working with Wolters Kluwer makes it possible to access evidence-based content that is backed by over 30 years of knowledge and experience, coupled with robust AI architectures,” said Jean-Claude Saghbini, Chief Technology Officer and President of Technology Services, Lumeris.