AstraZeneca Advances Ambition to Redefine Care for Blood Cancer at ASH 2021

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WILMINGTON, Del.– AstraZeneca will present new data underscoring its commitment to transforming hematologic cancer care at the 63rd American Society of Hematology (ASH) Annual Meeting and Exposition, December 11 to 14, 2021.

More than 25 abstracts will feature data across the Company’s hematology portfolio and pipeline, including new analyses from the CALQUENCE® (acalabrutinib) Phase III program such as an oral presentation of three-year follow-up data from the ASCEND Phase III trial in relapsed or refractory chronic lymphocytic leukemia (CLL).

Overall, data will span over 10 types of blood cancers and related conditions with a focus on CLL, mantle cell lymphoma (MCL), diffuse large B-cell lymphoma (DLBCL) and acute myeloid leukemia.

Dave Fredrickson, Executive Vice President, Oncology Business Unit, AstraZeneca, said: “Our robust CALQUENCE data at ASH will include an important new formulation designed to expand the pool of patients who may benefit from CALQUENCE. Moreover, data from three Phase III trials will show the sustained efficacy and safety of CALQUENCE, which is central to our commitment to prioritize the patient experience while providing long-term control of the disease in those with chronic lymphocytic leukemia.”

Anas Younes, Senior Vice President, Haematology R&D, AstraZeneca, said: “Testing new ways of overcoming drug resistance and continually pushing for better and deeper responses for patients are core focus areas of our early hematology portfolio. The preclinical data we are presenting at this year’s ASH meeting for capivasertib and AZD4573 add to the emerging body of evidence showing the potential for new approaches to become the cornerstones of tomorrow’s combination therapies for hard-to-treat blood cancers.”