MILFORD, Mass.– Waters Corporation has introduced its most advanced benchtop tandem quadrupole to date, the Xevo™ TQ Absolute XR Mass Spectrometer, at the 73rd ASMS Conference on Mass Spectrometry and Allied Topics. The new system raises the bar for robustness, sensitivity, and operational efficiency in high-throughput analytical labs.
Building on the success of its predecessor, the Xevo TQ Absolute, the XR model delivers up to six times greater robustness and resilience to contamination, reducing downtime and enhancing reliability in demanding testing environments. It is designed for laboratories focused on pharmaceutical quantitation, PFAS detection, and bioanalysis, where trace-level sensitivity and reproducibility are critical.
“This new generation Xevo is built for labs under increasing pressure from complex pharmaceutical needs and growing demand for PFAS testing,” said James Hallam, Vice President of Liquid Chromatography-Mass Spectrometry at Waters. “Its robustness and sensitivity help labs stay productive and deliver high-confidence results.”
Engineered with sustainability and space-saving in mind, the Xevo TQ Absolute XR uses up to 50% less power and nitrogen gas, generates less heat, and occupies half the bench space of comparable instruments. It features Waters’ latest StepWave™ XR Ion Guide, designed to minimize maintenance while maintaining high precision even in the most challenging matrices.
Early adopters report strong performance. Sally Hannam, Scientific Director at Synexa Life Sciences, highlighted the system’s reliability: “We’ve performed over 20,000 plasma sample injections with outstanding reproducibility and accuracy. This system gives us confidence in tackling increasingly complex bioanalytical challenges.”
The Xevo TQ Absolute XR also offers industry-leading out-of-the-box quantitation for negatively ionizing compounds like PFAS, making it an ideal solution for environmental, food safety, and pharmaceutical testing labs seeking both performance and efficiency.
With its compact design and advanced capabilities, Waters’ newest mass spectrometer positions itself as a next-generation solution for modern analytical laboratories.
